2 Corinthians 12:8: “Concerning this thing, I begged the Lord three times that it might depart from me.
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Meaning, Biblical Use & Significance

Exploring the Meaning of Aphistemi in Greek

ἀφίστημι aphistemi (af-is’-tay-mee) Verb

ἀφίστημι means “to leave” and appears 15 times in Scripture, including in Luke and Acts.

Core Meaning

ἀφίστημι is defined as “to leave.” In Luke 2:37 it describes not departing from the temple.

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Luke Occurrences

In Luke 4:13 the devil “departed from him until another time.” In Luke 13:27 it appears as the command, “Depart from me.”

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Acts Occurrences

In Acts 5:38 it is used as “withdraw from these men, and leave them alone.” In Acts 15:38 it describes someone who had “withdrawn from them.”

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ἀφίστημι expresses the act of leaving, whether as a physical departure, a withdrawal from people, or a turning away within a situation of testing. In the passages where it appears, it marks movement away from a place, a person, an affliction, or a former attachment.

2 Corinthians 12:8: “Concerning this thing, I begged the Lord three times that it might depart from me.

Occurrences

Luke 2:37: “and she had been a widow for about eighty-four years), who didn’t depart from the temple, worshiping with fastings and petitions night and day.”

Here ἀφίστημι is framed negatively (“didn’t depart”), highlighting sustained presence rather than motion. The word’s force is felt by contrast: the temple is the fixed point, and her life is described as refusing the normal pattern of leaving. The continued “worshiping with fastings and petitions night and day” interprets what this non-departure looks like in practice—her devotion is portrayed as staying put.

Key insight about Exploring the Meaning of Aphistemi in Greek

Luke 4:13: “When the devil had completed every temptation, he departed from him until another time.”

In this scene ἀφίστημι marks the end of a confrontation: after “every temptation” has run its course, the tempter leaves. The phrase “until another time” gives the departure a provisional quality; leaving is real and immediate, but not final. The verb therefore carries narrative momentum, closing one episode while leaving the possibility of renewed approach.

Luke 8:13: “Those on the rock are they who, when they hear, receive the word with joy; but these have no root, who believe for a while, then fall away in time of temptation.”

Here leaving is not spatial but relational: the ones described “believe for a while” and then “fall away” precisely when pressure comes (“in time of temptation”). ἀφίστημι portrays a movement away from an initial stance of reception and joy into separation from what was briefly held. The timing matters: the departure is triggered by the testing that exposes the lack of “root.”

Luke 13:27: “He will say, ‘I tell you, I don’t know where you come from. Depart from me, all you workers of iniquity.’”

In this saying the verb is an imperative—an enforced leaving. The command “Depart from me” sets a boundary of exclusion grounded in the speaker’s rejection (“I don’t know where you come from”). ἀφίστημι contributes the decisive severing of proximity: those addressed must move away from the speaker’s presence.

Acts 5:37: “After this man, Judas of Galilee rose up in the days of the enrollment, and drew away some people after him. He also perished, and all, as many as obeyed him, were scattered abroad.”

Here ἀφίστημι describes being “drawn away,” portraying departure as the effect of a leader’s pull. The leaving is social: “some people” are moved from their prior alignment to follow another. The aftermath—his perishing and the scattering of those who “obeyed him”—shows how a departure initiated by persuasion can dissolve under pressure and end in dispersal.

Acts 5:38: “Now I tell you, withdraw from these men, and leave them alone. For if this counsel or this work is of men, it will be overthrown.”

In this counsel ἀφίστημι functions as a strategic instruction to step back. “Withdraw from these men” and “leave them alone” portray leaving as deliberate restraint rather than flight. The motivation given (“if this counsel or this work is of men, it will be overthrown”) links withdrawal with allowing events to unfold without interference.

Acts 12:10: “When they were past the first and the second guard, they came to the iron gate that leads into the city, which opened to them by itself. They went out, and went down one street, and immediately the angel departed from him.”

Here leaving is swift and clear: after guiding the escape beyond guards and through the “iron gate,” the angel “immediately…departed.” ἀφίστημι punctuates the rescue narrative by marking the end of angelic accompaniment. The departure underscores that the assistance was purposeful and timed to the moment of deliverance.

Acts 15:38: “But Paul didn’t think that it was a good idea to take with them someone who had withdrawn from them in Pamphylia, and didn’t go with them to do the work.”

In this dispute ἀφίστημι identifies a prior withdrawal as a meaningful action with ongoing consequences. The one in view “had withdrawn from them” and this is interpreted in the same breath as “didn’t go with them to do the work.” Leaving the group is not merely travel; it is separation from a shared mission, and it shapes present judgments about reliability.

Acts 19:9: “But when some were hardened and disobedient, speaking evil of the Way before the multitude, he departed from them, and separated the disciples, reasoning daily in the school of Tyrannus.”

Here ἀφίστημι marks a conscious departure from hostile opposition. The leaving is paired with an organizing action: he “departed from them, and separated the disciples.” The verb thus signals a break with those “hardened and disobedient,” while the following clause shows the constructive outcome—continued teaching (“reasoning daily”) in a new setting.

Acts 22:29: “Immediately those who were about to examine him departed from him, and the commanding officer also was afraid when he realized that he was a Roman, because he had bound him.”

In this legal tension ἀφίστημι describes rapid disengagement: the would-be examiners “immediately…departed from him.” Their leaving is motivated by fear once his status is recognized, and the verb captures the abrupt change from readiness to interrogate to hurried withdrawal. Leaving becomes a protective reaction, distancing themselves from a potentially wrongful action already taken (“because he had bound him”).

2 Corinthians 12:8: “Concerning this thing, I begged the Lord three times that it might depart from me.”

Here leaving is cast as removal: something burdensome is asked to “depart from me.” The repeated pleading (“three times”) portrays departure as desired relief, not the petitioner’s movement but the movement of the “thing” away from the person. ἀφίστημι therefore naturally extends to the hoped-for lifting of an affliction.

1 Timothy 4:1: “But the Spirit says expressly that in later times some will fall away from the faith, paying attention to seducing spirits and doctrines of demons,”

In this warning ἀφίστημι marks a decisive shift of allegiance: “fall away from the faith” is linked with turning attention elsewhere (“paying attention to seducing spirits and doctrines of demons”). The departure is explained as a reorientation—leaving one commitment while giving heed to competing influences.

Guide to Exploring the Meaning of Aphistemi in Greek

Sense and Usage

Across these passages, ἀφίστημι consistently depicts leaving as a movement away from a reference point—sometimes a place (“the temple”), sometimes a person (“Depart from me”), and sometimes a prior attachment (“from the faith”). The verb is flexible about what “leaves”: in Luke 2:37 it is a person who does not leave a location; in Luke 4:13 and Acts 12:10 it is a personal agent who leaves another person; in 2 Corinthians 12:8 it is “this thing” whose departure is sought. This variety keeps the core idea intact while allowing different narrative subjects and objects.

The contexts also show different kinds of leaving. Some departures are temporary and tactical, as with the devil leaving “until another time,” or the examiners stepping away “immediately” when circumstances change. Others are portrayed as morally weighty separations: “fall away in time of temptation” and “fall away from the faith” treat leaving as a serious break that happens under pressure or deception. Still others are framed as prudent distance: “withdraw from these men, and leave them alone” presents leaving as restraint, and Acts 19:9 depicts leaving as a necessary separation in order to continue instruction without constant public opposition.

Finally, ἀφίστημι often functions to mark transitions—either in a story’s movement (departure after temptation; an angel leaving once the escape route is complete) or in relationships and communities (people drawn away after a leader; a co-worker’s prior withdrawal affecting future partnership). In each case, the verb identifies the point at which proximity, participation, or pressure is broken, whether by choice, command, persuasion, or plea.

Imagery

The imagery of ἀφίστημι in these texts frequently centers on distance created or removed. The temple scene pictures a life defined by not leaving; the escape scene pictures a helper leaving once the way is open; and the command “Depart from me” pictures exclusion by enforced separation. Even where the leaving is internal or communal—falling away under temptation, being drawn away after a leader, withdrawing from hostile opponents—the verb paints a line of departure that changes what comes next.

Sources: Lexical data from Strong’s Exhaustive Concordance and the Translators Brief Lexicon of Extended Strongs for Greek (STEPBible, CC BY). Occurrence data from the Translators Amalgamated Greek New Testament (STEPBible, CC BY). Scripture quotations from the World English Bible (public domain).

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